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Congrats Antara !!!

Antara’s winning image ‘Breaking symmetry’ is the cover image for Journal of Cell Science’s Special Issue: Imaging Cell Architecture and Dynamics. The image shows a mouse embryonic fibroblast labelled with phalloidin (actin – green), acetylated tubulin antibody (magenta) and DAPI (DNA – blue).   - LINK

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OBMT 2024
Fun meeting the promises to bring this community together every two years. The next meeting to happen in 2026 at NIISER, BBS. 
Congratulations

Radhika, Antara and Debasmita on your Best POSTER Prizes. 
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Kajal Singh

Congratulations to Kajal on being awarded the FEBS Trans-Youth Travel Fund grant and the @Infy_Foundation Travel Grant to attend the EMBO/FEBS 'Advanced Lecture Course on Molecular Mechanisms in Signal Transduction and Cancer'.Also for being picked to speak at the meeting. To know more - LINK

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Prachi Joshi

Congratulations, Prachi on being invited to present your work at the GRS symposium for two Gordon Conferences .Thanks, @Infy_Foundation, for supporting her travel.

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Congrajulations
Dr. Prachi Joshi

on successfully defending you thesis, making you the 7th student graduating from the lab. Good luck with everything ahead
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Congrajulations
Dr. Rajeshwari BR.

on successfully defending you thesis, making you the 6th student graduating from the lab. Good luck with everything ahead
Aug 3, 2023
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Madhavan Jayakrishnan

Spent the summer in the lab from ASHOKA University. He worked towards optimising quantitative image analysis for studies by Antara in the lab. Was great to have you Madhavan !

Piyush and Prashanth

The lab also saw Piyush and Prashanth joining the lab for the summer and staying on to continue their work in the lab.

Welcome aboard !!

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ICMR Grant

A one year extension to account for the time lost during COVID has allowed us to keep working on the ICMR grant to look at the AURKA-RalA crosstalk. 

SERB-CRG Grant

The lab was funded with a SERB-RG grant for studying Cell-matrix adhesion-dependent Golgi organisation in normal and anchorage-independent cancers.

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OMKAR, TARUN and NIKITA

from the lab all started their graduate school journeys in Turku, Utah and Vienna respectively.  Wishing them the very best going forward.

 

Click on photo to know more about their current labs.

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ARPITA

joined the lab for her Masters Thesis Dissertation from Fergusson College, Pune

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SRIVATHSA, TUSHAR, 

GRISHMA, MRIDUSHMITA

Joined the lab for for Semester Projects

 2022-23         

Dr. SIDDHI INCHANALKAR - Congratulations on successfully defending your thesis !!!

With a Masters from DY Patil University, Siddhi studies Ras-AURKA-Ral crosstalk in cancers.  She also works with the JK lab (IISER-Chem) to evaluate the delivery of AURKA inhibitor MLN8237 by nanovesicles. Siddhi is also an active doodler, and enjoys pencil charcoal painting and hopes to learn to play the violin some day.   

DEC 2020

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Thanks, DENTSPLY SIRONA for continuing to fund our research. This is much appreciated !!

DEC 2020

NOV / DEC 2020

Congratulations Natasha and Debasmita!

Their review looks at the role

phosphorylation of the tyrosine-14

residue (pY14Cav1) has in its function

in and out of caveolae. Cells that

experience significant mechanical

stress are seen to have abundant caveolae. They play a vital role in regulating cellular signaling and endocytosis, which could further affect the abundance and distribution of caveolae at the PM, contributing to sensing and/or buffering mechanical stress. Changes in membrane tension in cells responding to multiple mechanical stimuli affects the organization and function of caveolae. These mechanical cues regulate pY14Cav1 levels and function in caveolae and focal adhesions. This review, along with looking at the mechanosensitive nature of caveolae, focuses on the role of pY14Cav1 in regulating cellular mechanotransduction.

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•  Caveolin1 Tyrosine-14 Phosphorylation: Role in Cellular Responsiveness to Mechanical Cues. Natasha Buwa, Debasmita Mazumdar & Nagaraj Balasubramanian. The Journal of Membrane Biology (Nov 2020). Click Here. (NEW)

•  Adhesion‐dependent Caveolin1 Tyrosine‐14 phosphorylation is regulated by FAK in response to changing matrix stiffness

Natasha Buwa,  Nivedhika Kannan,  Shaunak Kanade &  Nagaraj Balasubramanian.  FEBS Letters ( Dec 2020). Click Here. (NEW)

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JULY 2020

Congratulations Keerthi, Omkar and Sailee!

Keerthi's work is now published as part of the series on "The Impact of Tumor Extracellular Matrix Cross-Talk on Cancer Hallmarks" in FRONTIERS of CELL and DEVELOPMENT BIOLOGY.

Cell Derived Matrix Fibulin-1 Associates With Epidermal Growth Factor Receptor to Inhibit Its Activation, Localization and Function in Lung Cancer Calu-1 Cells
Keerthi Harikrishnan , Omkar Joshi , Saili Madangirikar and Nagaraj Balasubramanian

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FEB 2020

Congratulations Keerthi !!!

Keerthi from the lab was awarded on the best poster awards at ISCSM 2020, for her poster entitled "Cell-Derived Matrix Fibulin-1 associates with Epidermal Growth Factor Receptor to regulate its activation, localization and function in lung cancer"  

International Symposium on Cell Surface Macromolecules. February 17-21, 2020, IISER Pune, NCL Pune 

BLOG

Research Internships: Where, When, And How?

This blog includes different aspects of choosing the right lab, writing the first email, responding to emails and making a strong CV/Resume.

JUN 29, 2020 | BY KARISHMA S. KAUSHIK , NAGARAJ BALASUBRAMANIAN, SNEHAL KADAM, OMKAR JOSHI

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Oct 2019

Keerthi

Tortuga

Philip

Sep 2019

Congratulations Siddhi !!!

Siddhi from the lab just won the best poster award in the drug delivery category for her work on "Nanovesicle-Mediated Delivery of MLN8237(Alisertib) Preferentially Inhibits Aurora Kinase A To Target RalA and Anchorage-Independent Growth in Breast Cancer Cells" at the TCGA meeting. Considering she wasn't sure if she can present till the day before, this was very cool !! The lesson for all of us here was that you can really be winning an award if you don't present :-) 

http://tcga.ctcr.in/

Sep 2019

Congratulations Rajeshwari and Prachi on successfully defending your comprehensive this month. Good luck with everything planned ahead !!

SEP 2019

Sep 2019

Congratulations Keerthi !!!

Keerthi and Venba from @AdhesionLab will be attending the EMBO | ASCB meeting in Dec at Washington DC thanks to a generous Travel Grant and Chilcare Grant from @ASCBiology. They are both looking forward to the same !! Thanks @ASCBiology @EMBO
 

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