Congrajulations
Dr. Rajeshwari BR.
on successfully defending you thesis, making you the 6th student graduating from the lab. Good luck with everything ahead
Aug 3, 2023
Madhavan Jayakrishnan
Spent the summer in the lab from ASHOKA University. He worked towards optimising quantitative image analysis for studies by Antara in the lab. Was great to have you Madhavan !
Piyush and Prashanth
The lab also saw Piyush and Prashanth joining the lab for the summer and staying on to continue their work in the lab.
Welcome aboard !!
ICMR Grant
A one year extension to account for the time lost during COVID has allowed us to keep working on the ICMR grant to look at the AURKA-RalA crosstalk.
SERB-CRG Grant
The lab was funded with a SERB-RG grant for studying Cell-matrix adhesion-dependent Golgi organisation in normal and anchorage-independent cancers.
OMKAR, TARUN and NIKITA
from the lab all started their graduate school journeys in Turku, Utah and Vienna respectively. Wishing them the very best going forward.
Click on photo to know more about their current labs.
ARPITA
joined the lab for her Masters Thesis Dissertation from Fergusson College, Pune
SRIVATHSA, TUSHAR,
GRISHMA, MRIDUSHMITA
Joined the lab for for Semester Projects
2022-23
Dr. SIDDHI INCHANALKAR - Congratulations on successfully defending your thesis !!!
With a Masters from DY Patil University, Siddhi studies Ras-AURKA-Ral crosstalk in cancers. She also works with the JK lab (IISER-Chem) to evaluate the delivery of AURKA inhibitor MLN8237 by nanovesicles. Siddhi is also an active doodler, and enjoys pencil charcoal painting and hopes to learn to play the violin some day.
DEC 2020
Thanks, DENTSPLY SIRONA for continuing to fund our research. This is much appreciated !!
DEC 2020
NOV / DEC 2020
Congratulations Natasha and Debasmita!
Their review looks at the role
phosphorylation of the tyrosine-14
residue (pY14Cav1) has in its function
in and out of caveolae. Cells that
experience significant mechanical
stress are seen to have abundant caveolae. They play a vital role in regulating cellular signaling and endocytosis, which could further affect the abundance and distribution of caveolae at the PM, contributing to sensing and/or buffering mechanical stress. Changes in membrane tension in cells responding to multiple mechanical stimuli affects the organization and function of caveolae. These mechanical cues regulate pY14Cav1 levels and function in caveolae and focal adhesions. This review, along with looking at the mechanosensitive nature of caveolae, focuses on the role of pY14Cav1 in regulating cellular mechanotransduction.
• Caveolin1 Tyrosine-14 Phosphorylation: Role in Cellular Responsiveness to Mechanical Cues. Natasha Buwa, Debasmita Mazumdar & Nagaraj Balasubramanian. The Journal of Membrane Biology (Nov 2020). Click Here. (NEW)
• Adhesion‐dependent Caveolin1 Tyrosine‐14 phosphorylation is regulated by FAK in response to changing matrix stiffness
Natasha Buwa, Nivedhika Kannan, Shaunak Kanade & Nagaraj Balasubramanian. FEBS Letters ( Dec 2020). Click Here. (NEW)
JULY 2020
Congratulations Keerthi, Omkar and Sailee!
Keerthi's work is now published as part of the series on "The Impact of Tumor Extracellular Matrix Cross-Talk on Cancer Hallmarks" in FRONTIERS of CELL and DEVELOPMENT BIOLOGY.
Cell Derived Matrix Fibulin-1 Associates With Epidermal Growth Factor Receptor to Inhibit Its Activation, Localization and Function in Lung Cancer Calu-1 Cells
Keerthi Harikrishnan , Omkar Joshi , Saili Madangirikar and Nagaraj Balasubramanian
FEB 2020
Congratulations Keerthi !!!
Keerthi from the lab was awarded on the best poster awards at ISCSM 2020, for her poster entitled "Cell-Derived Matrix Fibulin-1 associates with Epidermal Growth Factor Receptor to regulate its activation, localization and function in lung cancer"
International Symposium on Cell Surface Macromolecules. February 17-21, 2020, IISER Pune, NCL Pune
BLOG
Research Internships: Where, When, And How?
This blog includes different aspects of choosing the right lab, writing the first email, responding to emails and making a strong CV/Resume.
JUN 29, 2020 | BY KARISHMA S. KAUSHIK , NAGARAJ BALASUBRAMANIAN, SNEHAL KADAM, OMKAR JOSHI
Oct 2019
Keerthi
Tortuga
Philip
Sep 2019
Congratulations Siddhi !!!
Siddhi from the lab just won the best poster award in the drug delivery category for her work on "Nanovesicle-Mediated Delivery of MLN8237(Alisertib) Preferentially Inhibits Aurora Kinase A To Target RalA and Anchorage-Independent Growth in Breast Cancer Cells" at the TCGA meeting. Considering she wasn't sure if she can present till the day before, this was very cool !! The lesson for all of us here was that you can really be winning an award if you don't present :-)
Sep 2019
Congratulations Rajeshwari and Prachi on successfully defending your comprehensive this month. Good luck with everything planned ahead !!
SEP 2019
Sep 2019
Congratulations Keerthi !!!
Keerthi and Venba from @AdhesionLab will be attending the EMBO | ASCB meeting in Dec at Washington DC thanks to a generous Travel Grant and Chilcare Grant from @ASCBiology. They are both looking forward to the same !! Thanks @ASCBiology @EMBO
