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CELL ADHESION LAB

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CONTACT

Dr. Nagaraj Balasubramanian

Dr. Homi Bhabha Road,

Pashan, Pune : 411008,

Maharashtra, INDIA

Tel No. : +91 (20) 25908202

Email. : adhesion.lab(at)gmail.com

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RESEARCH INTEREST OF THE LAB

We are interested in understanding how the cell-matrix microenvironment affects what cells do. Cell-matrix interactions and their regulation of membrane trafficking, organelle architecture and signalling. Further, our studies test how this regulation is deregulated cancers to make cell anchorage-independent. We are aiming to target these deregulated pathways to restore anchorage-dependence in cancers. We also study how adhesion-dependent trafficking and signalling is different in 2D vs 3D microenvironment and how cells interact and behave with implants in a 3D microenvironment.

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Congratulations Dr. Kajal Singh
On successfully defending your thesis.
8th Graduating student from the lab.

Congratulations Dr. Debasmita Mazumdar
On successfully defending your thesis.
9th Graduating student from the lab.

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NEW LAB PUBLICATIONS

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LAB JOURNAL COVERS

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Oct 2024
Antara’s winning image ‘Breaking symmetry’ is the cover image for Journal of Cell Science’s Special Issue: Imaging Cell Architecture and Dynamics.

The image shows a mouse embryonic fibroblast labelled with phalloidin (actin – green), acetylated tubulin antibody (magenta) and DAPI (DNA – blue).

Image Credit : Antara

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Jan 2026
The image shows a wild-type mouse embryonic fibroblast treated with ROCK inhibitor Y-27632 and embedded in 1.0 mg/mL 3D collagen gel. The cell is labeled with phalloidin for actin (purple), and the collagen is imaged by reflectance (yellow).

Image credit : Debasmita

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Jan 2026
Differential Golgi phenotypes in breast cancer cells. MCF7 cell populations exhibit contrasting Golgi organisations, with either a disorganised Golgi (as seen on the left) or a more compact organised Golgi (as seen on the right). Phalloidin-labelled actin (yellow), DAPI-stained nuclei (cyan) and GalTase–RFP-labelled trans-Golgi (magenta) reveal the differential Golgi organisation in MCF7 cells.

Image Credit : Arnav

PAST and CURRENT FUNDERS OF THE LAB

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